- Tipo de expresión:
- Doctorado: Propuesta de dirección de tesis doctoral/temática para solicitar ayuda predoctoral ("Hosting Offer o EoI")
- Ámbito:
- mecanismos generales de tumorigéneis
- Área:
- Vida
- Modalidad:
- Convocatorias autonómicas
- Referencia:
- 2023
- Centro o Instituto:
- CENTRO DE BIOLOGIA MOLECULAR SEVERO OCHOA
- Investigador:
- GINES MORATA PEREZ
- Palabras clave:
-
- JNK, senescence, chromatin, growth
- Documentos anexos:
- 584218.docx
PREDOC2023 (CM)
The main focus of our research is the study of tumorigenesis, a phenomenon of great scientific and societal relevance. Because of its sophisticated genetic technology and other experimental advantages, we are using the imaginal discs of the fruitfly Drosophila melanogaster as a model system to investigate molecular and genetic factors behind the appearance and development of tumors. We are focusing on three research lines:
1) the tumorigenic potential of cells that cannot execute the apoptosis program.
2) Chromatin modifications of senescent cells and reversibility of senescence.
3) Interactions among cell populations with different growth rates.
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