Pancreatic islets and stem cells

Research group included in Stem Cell Department (CABIMER). The activities of the group fit with the strategic plans and field of interest of the National Health System. The main aim of the group is to contribute to the knowledgement of the pancreatic beta cell biology and pathophysiology from a basic point of view and to translate this knowledgement to diabetes cell therapy. To achieve this general aim the research work is focused in three principal research lines. i) study of the transcriptional factors and molecular mechanisms involved in pancreas development and physiology; ii) the generation of insulin producing cells from pluripotent stem cells and iii) to awake the regeneration and proliferation mechanisms of pancreatic beta cells.