BIOORGANIC AND SUPRAMOLECULAR CARBOHYDRATE CHEMISTRY GROUP

The Research team focus the activity under the motto “Carbohydrates for Health and Wellness: Glycodrugs, Glycotransportes and Glycobiotics”. The research activity is framed along three different axis: (i) glycosidase inhibitors and pharmacological chaperones for the treatment of rare diseases (lysosomal storage disorders such as Gaucher and Fabry diease or GM1 Gangliosidosis) and cancer, (ii) cyclodextrin-based drug delivery systems for active agents (from small drugs to macromolecular therapeutics), and (iii) preparation and analysis of oligosaccharides with prebiotic and nutraceutical activity, and their application to the prevention and treatment of intestinal inflammatory diseases (Crohn disease and ulcerative colitis).