Technological offer

A new immunotherapy strategy based on the administration of ADCs or CAR-T cells derived from a monoclonal antibody specific for the pre-TCR receptor, which impairs LIC activity and tumor progression, has been developed and validated in a preclinical human T-ALL xenotransplantation model in mice.

Novel compounds based on a repurposed drug to combat gram (+) bacterial infections.

New family of molecules derived from Isoquercetin for the treatment and/or prevention of inflammatory and degenerative eye diseases.

Novel Hydrogel with optimized mechanical and structural properties to resemble artificial lymph nodes and improve primary human CAR-T cell manufacture.

Compounds useful as reversible light-regulated agonists for activation of Vitamin D receptor (VDR) using wavelengths suitable for phototherapy, that would avoid the appearance of secondary effects, with application for the treatment of diseases that involve an alteration of the VDR function.

A recombinant gluten degrading protein that may have application as an agent or food additive for the prevention of gluten-mediated conditions, as well as in the food industry for the manufacturing of gluten-free products.

New family of molecules (low-molecular weight peptides) present in olive oil with blood pressure-reducing activity for hypertensive people

Design of a novel proteolytic set of chimeras (26STACs) directed at the degradation of the ceramide transfer protein CERT-1 by the proteasome, in an E3-independent manner, for its use in the treatment of breast cancer.

Effective triple-negative breast cancer treatment based on the modulation of the phenotype of CD206+ tumor associated macrophages by means of a novel peptide-drug-conjugate (PDC) which is able to slow tumor progression and supress lung metastasis.

Novel DNA probes useful for the rapid detection of SARS-CoV2, influenza and respiratory syncytial viral RNAs. Integrated in different set of devices, these probes enable the detection of RNA sequences in few minutes, without the need for RNA extraction, purification and PCR amplification