New antivirals, synthesized using green chemistry and administered by inhalation, capable of combating respiratory diseases and enveloped viruses.
Small molecule that stabilizes the retromer complex, showing strong neuroprotective effects in highly excitotoxic conditions and maintaining key neuronal survival proteins like KIDINS220 in validated in‑vitro models.
Programmable electronic device designed to reduce pathological tremor through personalized superficial stimulation of peripheral nerves, optimizing motor control without invasive procedures, calibrated to the individual patient.
Compounds that inhibit tau and tubulin kinase (TTBK1) for use in the treatment and/or prevention of neurodegenerative diseases in which this enzyme is involved.
System that enables the measurement and verification of the radiation dose received by a patient following proton or helium ion therapy. It uses PET and the natural production of F-18 in tissues, offering applications in oncology and clinical safety.
A Penicillium chrysogenum strain has been modified to produce high yields of the antifungal protein PdAfpB, enabling the possibility to use this protein in agricultural, food and pharma industries.
Novel Folate Receptor alpha (FRα) binding peptides induce brain cell reprograming and rejuvenation, enhancing cognitive function in aged mice. These unique peptides are able cross the blood-brain barrier and specifically bind to neuroepithelial FRα.
Penicillium strain that produces a highly active antifungal protein (AFP), namely PeAfpA, which is effective against pathogenic and food spoilage fungi. The strain has also been modified to eliminate its antibiotic resistance genes, ensuring its safe use in agriculture, food, and biomedical applications.
New compounds to treat parasitic diseases such as Chagas disease, leishmaniasis and trypanosomiasias. These derivatives act on a new target: G-cuadruplex DNA
Compounds useful as reversible visible-light-regulated antagonists for the localized and temporally restricted activation of beta-adrenoceptors, with application for the treatment of ocular diseases such as glaucoma.