Programmable medical device for pathological tremor reduction

Programmable electronic device designed to reduce pathological tremor through personalized superficial stimulation of peripheral nerves, optimizing motor control without invasive procedures, calibrated to the individual patient.

Market need: Pathological tremor is the most common movement disorder and a defining clinical characteristic of essential tremor and Parkinson’s disease. Current estimates suggest that essential tremor affects around 25 million individuals worldwide, while Parkinson’s disease is expected to impact more than 12.9 million people globally by 2040.
Despite its high prevalence, current treatments to pathological tremor are often invasive, costly, or insufficiently effective.

Proposed solution: Non-invasive system solution for reducing pathological tremor in a consistent and safe way that can avoid the side effects of direct brain stimulation and potentiate the effects of peripheral electrical stimulation to reduce tremor to more than a few minutes post stimulation. Preliminary results showed that tremor reduction observed in response to customized peripheral electrical stimulation in patients with essential tremor is mediated by complementary adaptations at two levels of the nervous system: (i) decreased spinal excitability and (ii) reduced descending tremorgenic drive at the supraspinal level.

Competitive advantages

Portable electronic sleeve capable of providing personalized peripheral electrical stimulation and suitable for home use.
Allows long‑term treatment and monitoring.
The device is effective, affordable, non‑invasive, and scalable.