New bacterial strain with a high capacity to capture CO2 and transform it into added-value nanocellulose. In addition, it produces nanocellulose from different types of agro-industrial waste, including crude glycerin residue from biodiesel production, sugar molasses, whey, etc...
The amplifier consists in a novel array of Josephson junctions and other superconducting elements that give rise to parametric amplification of microwave radiation with all desired properties for quantum computation: large gain, directional, broadband, near quantum-limited noise, tolerant to fabrication disorder and stable.
Design of a novel proteolytic set of chimeras (26STACs) directed at the degradation of the ceramide transfer protein CERT-1 by the proteasome, in an E3-independent manner, for its use in the treatment of breast cancer.
Effective triple-negative breast cancer treatment based on the modulation of the phenotype of CD206+ tumor associated macrophages by means of a novel peptide-drug-conjugate (PDC) which is able to slow tumor progression and supress lung metastasis.
Novel DNA probes useful for the rapid detection of SARS-CoV2, influenza and respiratory syncytial viral RNAs. Integrated in different set of devices, these probes enable the detection of RNA sequences in few minutes, without the need for RNA extraction, purification and PCR amplification
New tiourea- and urea-based glycolipids with immunomodulatory activity. The compounds are Mincle agonist and have shown in vitro and in vivo immunostimulant activity. They can be used as vacine adjuvants, in the modulation of the immune response and in the treatment of infectious disease or cancer.
Novel antiviral strategy targeting viral non-essential proteins (NEPs), scarcely prone to adaptive mutations. As a proof of concept, SARS-CoV-2 ORF9b homodimerization inhibitors have been identified that prevents the virus hyperinflammation response.
This device provides a suitable method for the capture, detection and identification of whole airborne biological particles, including viruses (such as SARS-CoV-2) and other pathogens.
Andrographolide derivatives for its use as treatment for inflammatory diseases related to cytokine storm.
Method to generate physical unclonable functions (PUFs) which uses acousto-optic systems. System that allows to reduce complexity while maintaining high integrability and reliability. Allows miniaturization.