New antiviral compound against HSV-1 and HSV-2 that can be used in combination with other drugs or to treat resistant strains to conventional antivirals.
Enhanced knife that enables customizable thinning of hides during the tanning process, offering both protection and adjustable thickness. It is simple to use, features no moving electrical parts, and is highly safe for the user.
Selective SGK1 kinase inhibitors, blood-brain barrier-permeable, as drug candidates for the treatment of neurodegenerative diseases (such as Parkinson’s or Alzheimer’s disease) or cardiovascular diseases (such as hypertension).
New family of compounds with demonstrated in vitro efficacy against intracellular parasites responsible for leishmaniasis and American trypanosomiasis or Chagas disease. Pharmacokinetic and toxicity studies have been conducted in rats, as well as preliminary efficacy studies in a murine model.
Novel peptide-based compounds for the treatment of cardiovascular diseases, including ventricular arrhythmias in patients with heart failure and hereditary syndromes characterized by reduced function of sodium or potassium ion channels.
An in vitro screening method by NMR spectroscopy of potential therapeutic compounds for Congenital Central Hypoventilation Syndrome (CCHS). The method is based in the identification of active agents that inhibit secondary structure changes in PHOX2B transcription factor.
An in vitro fluorescent method for early detection of Amyotrophic Lateral Sclerosis (ALS) and other TDP-43 related proteinopathies, such as Fronto Temporal Lobar Degeneration (FTLD), based on detection of pathological aggregates of TDP-43 present in cerebrospinal fluid.
Supported photocatalyst based on titanium oxide (TiO2) that allows remediation of pesticides in half the time than commercial ones. In addition, it is effective for the elimination of microorganisms. It is therefore ideal for the decontamination and disinfection of aqueous effluents.
Analysis of TAF1 isoforms in blood and cerebrospinal fluid of controls and individuals with Multiple Sclerosis.
Novel nickel-based catalyst that offers long-lasting catalytic activity under high temperature exposure and high efficiency for multi-cycle glycerol reforming processes.