Technological offer

New tiourea- and urea-based glycolipids with immunomodulatory activity. The compounds are Mincle agonist and have shown in vitro and in vivo immunostimulant activity. They can be used as vacine adjuvants, in the modulation of the immune response and in the treatment of infectious disease or cancer.

Novel antiviral strategy targeting viral non-essential proteins (NEPs), scarcely prone to adaptive mutations. As a proof of concept, SARS-CoV-2 ORF9b homodimerization inhibitors have been identified that prevents the virus hyperinflammation response.

Andrographolide derivatives for its use as treatment for inflammatory diseases related to cytokine storm.

Portable diagnostic device for the detection of analytes in biological samples. The biosensor allows a label-free quantitative detection. Simple use, no qualified personnel needed.

Low-cost method with high effectiveness for the diagnosis and prognosis of thyroid cancers that are difficult to resolve during preoperative evaluation. It provides a malignancy score measuring the methylation level of various CpG sites determined by a machine learning classification system.

Polysaccharides, mimics of heparan sulfates present in cells, that are effective in treatment and prevention of viral infections. They act as a decoy trap to prevent the virus from adhering to epithelial cells, thus slowing down the process of infection, and by directly inactivating the viral particles.

A conjugate of fatty acids and amino acids has been found to protect neurons and facilitate the removal of protein aggregates that cause the most common neurodegenerative diseases. This opens the possibility of new, more effective and cheap treatments.

New carbon nanocapsules filled with enriched lithium compounds that can be applied in NCT for cancer treatment

Live attenuated vaccine incorporating a variant of the Rift Valley Fever virus obtained in the laboratory by serial passages in the presence of a mutagenic agent, that could be the basis of a new vaccine strain with safety parameters not previously described.

System based on an algorithm that allows for highly accurate diagnosis of breast cancer through the analysis of stochastic intracellular fluctuations of tumor cells, using images obtained through digital microscopy.