Our group studies the regulation of the structure and function of Arabidopsis thaliana telomeres and is integrated since it started by Dr. Miguel Ángel Vega Palas and by María Isabel Vaquero de Sedas, who has a bachelor degree in Biology. In 2021 we got a Spanish grant that included three people: María Isabel Vaquero de Sedas, María Dolores Cubiles de la Vega, Full Professor of Statistics at the University of Seville and Doctor in Informatics, and myself, Miguel Ángel Vega.

R&D of new drugs for the treatment of neurological diseases, with high traslatational contens. Multidisciplinary group (chemistry, pharmacy and biology) with experience in chemoinformatics, organic synthesis, biological screening, ADMETox properties optimization and technology transfer. Our projects offer new candidates for medicines and knowledge on innovative targets with clear therapeutic potential for unmet diseases such as Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS), depression, stroke, etc.

Theoretical study of physico-chemical properties of molecules with biological interes

The Antiparasite Chemotherapy group develops the research line "New chemical entities for drug discovery" in the field of parasitic diseases, especially those produced by pathogenic protozoa. Since its creation in 2005, the group has developed several series of compounds that are highly active against various parasitic protozoa (T. cruzi, T. brucei spp., T. vaginalis, Leishmania spp., Plasmodium spp.). Several lead compounds also demonstrated in vivo efficacy in mouse models of trypanosomiasis, leishmaniasis, and malaria.

The research of the group is focused on the endocannabinoid system and / or related biological targets. This research requires a strong collaboration with national and international pharmacologists. In the last years, this research has been awarded several prizes [Honorific Mention Research Award of Esteve Foundation 2016; Finalist Lilly XXIII doctoral award (2015); Best Publication 2016 of SEIC; Award 2018 from RANF] and has been continuously financed by National Plan projects.

The research group, founded in 1989, is composed, among others, by 6 permanent staff members. Carries out highly innovative, multidisciplinary, and cutting-edge research in the field of Medical Chemistry.

Group of reference and pioneering in Spain in peptidomimetics. Our research requires coordinated use of molecular modeling, synthetic methodologies in solution and solid-phase (peptides/small molecules) and biological evaluation. Experience in enzymatic inhibitors, mimetics of analgesic and antitumor peptides, and of neuropeptides.

The Processing and Mechanical Properties research group, called PROMECO, develops its research work on issues related to mechanical properties (creep, superplasticity and deformation mechanisms), processing, forming and manufacturing (forging, rolling, extrusion, friction stir, additive manufacturing , torsion, and modelling), and microstructural characterization (optical, scanning and transmission electron microscopy, texture and microtexture) of advanced high value added metallic materials.

This team comprise researchers with a multidisciplinary background (microbiologist and chemistry). Thus, the techniques available to the Research Group cover different subfields within the Area of Science and Technology of Foods. Among others may be mentioned the following: Classical Techniques Microbiology, Molecular Biology, Analytical Chemistry, Biochemistry, Omics, Food Technology fermented, optical and scanning microscopy, statistical, and predictive microbiology.

The team includes three chemists (Brenes, García, Romero), one biochemists (Medina) and one food technologist (Ramírez). The team has investigated together for over 15 years and has worked with other teams of Instituto de la Grasa, University of Seville, IFAPA, and research centers in the USA, Italy, Turkey, Peru and Algeria.