This device provides a suitable method for the capture, detection and identification of whole airborne biological particles, including viruses (such as SARS-CoV-2) and other pathogens.
Novel antiviral strategy targeting viral non-essential proteins (NEPs), scarcely prone to adaptive mutations. As a proof of concept, SARS-CoV-2 ORF9b homodimerization inhibitors have been identified that prevents the virus hyperinflammation response.
New tiourea- and urea-based glycolipids with immunomodulatory activity. The compounds are Mincle agonist and have shown in vitro and in vivo immunostimulant activity. They can be used as vacine adjuvants, in the modulation of the immune response and in the treatment of infectious disease or cancer.
Effective triple-negative breast cancer treatment based on the modulation of the phenotype of CD206+ tumor associated macrophages by means of a novel peptide-drug-conjugate (PDC) which is able to slow tumor progression and supress lung metastasis.
Design of a novel proteolytic set of chimeras (26STACs) directed at the degradation of the ceramide transfer protein CERT-1 by the proteasome, in an E3-independent manner, for its use in the treatment of breast cancer.
The amplifier consists in a novel array of Josephson junctions and other superconducting elements that give rise to parametric amplification of microwave radiation with all desired properties for quantum computation: large gain, directional, broadband, near quantum-limited noise, tolerant to fabrication disorder and stable.
New bacterial strain with a high capacity to capture CO2 and transform it into added-value nanocellulose. In addition, it produces nanocellulose from different types of agro-industrial waste, including crude glycerin residue from biodiesel production, sugar molasses, whey, etc...
New plant-based compounds for use as biostimulants in sustainable agriculture. Ideal for improving the activity of arbuscular mycorrhizal fungi and mycorrhization in plants.
A recombinant gluten degrading protein that may have application as an agent or food additive for the prevention of gluten-mediated conditions, as well as in the food industry for the manufacturing of gluten-free products.
Compounds useful as reversible light-regulated agonists for activation of Vitamin D receptor (VDR) using wavelengths suitable for phototherapy, that would avoid the appearance of secondary effects, with application for the treatment of diseases that involve an alteration of the VDR function.