CDK regulation of the meiotic nuclear biology
CDK regulation of the meiotic nuclear biology
The World Health Organization (WHO) considers infertility as a disease, and estimates 1-2% of prevalence in couples in developed countries (3.6 million of infertile couples in high-income regions). A key feature of meiosis, the cellular program that generates gametes, is the recombination between homologous chromosomes (maternal and paternal) that, in addition to generate genetic diversity, facilitates accurate chromosome segregation.