Our group brings over 15 years of experience in stem cell research. Currently, our scientific program aims to investigate the dynamic properties of stem cells, including MSCs, to improve their therapeutic potential. In addition, we explore the use of stem cells for the treatment of central nervous system diseases.

We employ high-resolution cryo-electron microscopy (cryo-EM), in combination with functional experiments, to uncover the structure and mechanism of action of macromolecular protein complexes involved in human disease. The goal of our research is to open new therapeutic avenues by understanding the role of these protein complexes in pathogenesis.

We aim to understand the role of membrane mechanics and protein dynamic involve in different cell process, especially, we are focus on immunological synapse, viral infection and ebriogenesis. We use a wide range of systems (in-vitro to embryos) and technics, particularly HS-AFM and Fast-FLIM.

ENMA¿s group (Assembly of Materials and Surface Modification) has wide experience in the assembly of organic, inorganic or hybrid materials using the Langmuir-Blodgett (LB), self-assembly (SA), electrografting or spin-coating techniques and their characterization by spectroscopic, microscopic or electrochemical techniques, as well as in the modification of surfaces through physicochemical processes ((super)-hydrophobicity / hydrophilicity), or formation of nanostructures.

LEMA research group activities include several research lines based on the application of different laser technologies to modify materials. These include development of new materials with technological interest in different industrial sectors. The latter are related with higher efficiency and cleaner energy and based on environmentally respectful new processing techniques.

The group’s research is focused on the theoretical investigation of excited state reactivity and dynamics in complex molecular systems. We use theory and simulation to characterize fundamental aspects of the photophysics and photochemistry of these systems with emphasis on charge and energy transfer and transport processes in novel materials with applications to nanoelectronics, organic photovoltaics, and lighting.

We are devoted to the functional and biochemical characterization of DNA replication and repair enzymes. For that, we work with diverse biological systems, from very simple ones like bacterial viruses or genetic mobile elements, and also prokaryotic and eukaryotic cells. Our current efforts are focused in B-family DNA polymerases, in particular in the piPolB subfamily ("primer-independent PolBs), recently reported and characterized in our laboratory.