Involution of the CNS in the normal and pathological senility

Study of central and peripheral markers of neurodegenerative diseases. The research group work deals with the study of both the normal and the pathological involution markers of the Central Nervous System (neuronal and glial central biomarkers as well peripheral ones) in order to explain the pathogeny of neurodegenerative disorders and to open new therapeutical lines. Studies are carried out in a multidisciplinary approach, using morphological, histochemical and biochemical methods. Human Alzheimer`s and Creutzfeldt-Jakob¿s Diseases, sheep scrapie and experimental models of Alzheimer and CNS Oxidative Stress are mainly studied.