Coronavirus: replication, virus-host interactions, and protection

Our group is interested in the molecular basis of replication, transcription, and virus-host interactions of human respiratory coronaviruses (CoVs) using the severe and acute respiratory syndrome virus (SARS-CoV) and the Middle East respiratory syndrome CoV (MERS-CoV) as models. The impact of the infection by these viruses on the host, and the identification of signaling pathways modified by their viruses, are being studied in order to control disease.