Research and development in methods and technologies related to the study of protein expression in humans and other organisms.

The Neurobiology Unit investigates molecular mechanisms of neuronal death with the aim of identifying targets for therapeutic intervention in neurodegenerative diseases. Our team is also part of CIBERNED. The general lines of research are: 1) Molecular mechanisms of synapse elimination in models of Alzheimer's disease, 2) Regulation of mitochondrial DNA transcription and replication in genetic models of neurodegeneration. 3) Mitochondrial DNA as a biomarker in early stages of Parkinson's disease. This last line financed by the Michael J. Fox Foundation.

In our research group we are studying neuroinflammation in the context of neurodegenerative diseases and acute neuronal damage. It is suggested that neuroinflammation, in which activated glial cells (mainly microglia) are involved, play a role in the etiopathogenesis and/or in the progress of these pathologies. Our working hypothesis is that the modulation of neuroinflammation/glial activation can be a therapeutic strategy to act against the neuronal damage that occurs in neurodegenerative diseases and acute neuronal damage.

Study of pathological processes related to inflammation, fibrosis and tissue regeneration. Our research group focuses on the study of the regulatory mechanisms of inflammation and fibrosis using models of pancreatic and pulmonary pathologies. In particular, acute pancreatitis and idiopathic pulmonary fibrosis (IPF).

The group investigates the theoretical, computational, and implementation challenges arising in the design, construction, and control of complex robotic systems. Among these systems, we highlight parallel robots, anthropomorphic robotic arms, intelligent prostheses, biomechanical systems for motion assistance or rehabilitation, and other robots with diverse topologies that—thanks to sufficient sensing and adaptive capabilities—can interact with humans in an agile and safe manner.

The Research team focus the activity under the motto “Carbohydrates for Health and Wellness: Glycodrugs, Glycotransportes and Glycobiotics”.

The research carried out in the AS@FUN group can be divided into two main axes: (i) Design, Synthesis and Bioapplication of Functional Nanosystems and (ii) Asymmetric synthesis. All these subjects have in common the utilization of carbohydrates either as inexpensive chiral codifying agents or as molecular recognition elements of biological receptors implied in unsolved pathological processes.

Fundamental and applied studies on Coordination and Organometallc Chemistry oriented towards the development for new processes, such as olefin polymerization, or selective transformations renewable chemical feedstocks, that are of high interest for the Chemical Industry

The IREC Toxicology group was created in mid-2003 and since then it works on the evaluation of exposure to different types of toxicants in wildlife and livestock, as well as the effects they can have on the individuals, in the conservation of populations and the use of these natural resources. In this respect, we also study food safety implications that this type of contamination poses to human consumers. The knowledge obtained allows to develop strategies for risk reduction and perform better overall use of natural resources.

Our general aim is to understand the molecular mechanisms that control the generation of the different neuron subtypes of the nervous system