Virus-Host Interactions group

This group develops virus-host interaction analysis applied to emerging viruses of concern from their economic, sanitary, and environmental impact. Proteomics and transcriptomics are used to identify gaps and develop preventive and therapeutic strategies against epizootic and zoonotic viruses from a "One Health" perspective. We are interested in the molecular mechanisms of viral pathogenesis and immune response mechanisms. From the wide cellular systems and signaling pathways interacted by viruses, our research has shown potential intervention targets at the viral entry level, intracellular traffic, membrane lipid exchange, ER stress, autophagy, and apoptosis, especially concerning the African swine fever virus (ASFV) but also human viruses such as Ebola and SARS-CoV2 virus. In these we are developing biotechnology applications, such as antiviral compounds, and nanoparticles.