Lipids and Cardiovascular Pathology

Study of the pathophysiological role of LRP1 in the cardiovascular system. Molecular mechanisms involved in the modulation of LRP1 expression and…

Vascular biology, atherosclerosis and cardiovascular remodeling

The major research activity of this group addresses the study of the vascular biology as well as the cellular and molecular mechanisms involved in…

Pancreas and Liver Development and Disease

Defects in organogenesis or function of liver and pancreas lead to debilitating diseases, including diabetes and cirrhosis. Understanding the…

Metabolism and Cell Signaling

Our team investigates how cellular metabolic and bioenergetic fluxes interact with signaling processes to coordinate the growth and normal…

Cancer molecular targets

Our group is focused on the molecular mechanisms driving cancer progression, with particular emphasis in pancreatic cancer. This tumor, in particular…

Cardiac rhythm and contraction

Our group focuses on patho-physiological aspects of cardiac excitation-contraction coupling and arrhythmogenesis. Our goal is to improve the…

Molecular Oncology and Targeted Therapies

DNA damage response during meiosis

Transcription and mRNA processing

Replication and nuclear Dynamics

The organization of the genetic information in the form of chromatin is critical for cell function since the winding of the DNA around nucleosomes…