Inner Ear Development and Regeneration

We are interested in several aspects of the physiology and pathofisiology of the auditory organ, including its development, damage and degeneration…

Development and degeneration of the nervous system

In our laboratory we aim at understanding the mechanisms underlying NERVOUS SYSTEM development, understanding DEVELOPMENT as the whole process in an…

Splicing and genetic susceptibility to cancer

Pre-mRNA processing or splicing is an essential step of eukaryotic gene expression, where the spliceosome removes introns and exons are sequentially…

Molecular Genetics of Hereditary Cancer

The group launched the molecular diagnosis of breast / ovarian cancer and hereditary colorectal cancer using the technique HA_CAE. In addition to the…

Gene targeting

Study of the experimental conditions that will increase the frequency of gene targeting in human cells by testing different viral vectors and…

Cancer pathobiology: inter-, intra-tumoral heterogeneity and Molecular Targets

Molecular genetics, genomics, transcriptomics and cell biology of thyroid cancer genesis, maintenance and progression, with especial emphasis on…

Pancreas and Liver Development and Disease

Defects in organogenesis or function of liver and pancreas lead to debilitating diseases, including diabetes and cirrhosis. Understanding the…

Metabolism and Cell Signaling

Our team investigates how cellular metabolic and bioenergetic fluxes interact with signaling processes to coordinate the growth and normal…

Molecular Oncology and Targeted Therapies

DNA damage response during meiosis