Chromatin Modifications

The genetic information in eukaryotic cells is tightly wrapped around histone proteins to form chromatin, which is highly repressive to processes…

Ubiquitin (-like) signaling and Proteomics

Biocolloids and neutron scattering

The study of the relationship between the composition, structure and functionality of relevant biocolloids and nanoparticles in biology, pharmacy and…

Replication and endogenous DNA damage

Metabolic Regulation and Signaling in Cancer

Computational Epigenomics and Cell Identity

How can one genome encode for so many different cell types and functions? All cells of a multicellular organism (like us humans) share the same…

Metabolism, Immunology and Cardiovascular Risk

Structural biology of virus-host interactions

We use cryo-electron microscopy, combined with other structural and molecular biology approaches, to characterise macromolecular assemblies and…

Neuronal Excitability

Our overall aim is to understand the nanoscale physiology of the brain. Hereunder the role of the brain extracellular space (ECS) in signalling and…

Membrane Trafficking

The Membrane Trafficking Laboratory, led by Ikerbasque Research Professor Aitor Hierro at the Biofisika Institute (CSIC-UPV/EHU) in Leioa, Spain,…