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During their life cycle, fungi are able to change their morphology in response to environmental conditions. Our group is interested in the…
Our research interests lie at the interface between Chemistry and Biology. We apply Molecular Modeling and Computational Chemistry to the…
We are major contributors to the growing realization that hundreds of thousands of small ORFs (smORFs) of 10 to 100 amino-acids (aa) exist in every…
Understanding the mechanisms that preserve the integrity of eukaryotic genomes during chromosome replication, thus counteracting the accumulation of…
Our group uses the mouse limb skeleton as an experimental system to study the molecular and cellular mechanisms that coordinate morphogenesis and…
Our group is interested in elucidating the cellular principles and molecular mechanisms that govern vascular and immune responses during inflammation…
In the last decades, the mouse model tremendously contributed to the progress of research in immunology. The need for translational immunological…
Our group is interested in understanding how macromolecular machines control essential cellular functions. We rely on a blend of cryo-electron…
Our group studies regulatory mechanisms of key signalling switches controlling growth and adhesion signals, which regulate important cellular…
In vivo implementation and optimization of different CRISPR-Cas systems using zebrafish as model system.
Applying CRISPR-Cas and other molecular and…