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Characterization of the development, composition and function of the renal filtration system and its pathological anomalies using animal models (…
To elucidate the stoichiometry of the TCR. Study the mechanisms of assembly and intracellular retention. Discern between the specific and redundant…
Glycosylation is a complex post-translational modification that generates diverse glycans, contributing to the functional diversity of proteins. Our…
Our group has demonstrated experience in the functional characterization of surface proteins on tumour, leukocytic and endothelial cells, that have…
Mechanisms of infected cell recognition and in vivo control of viral infections by CD8+ cytotoxic T lymphocytes and use in vaccine development.
Our research focuses on the role of TCFL5, a bHLH transcription factor, in colon cancer cells. Deletion of TCFL5 significantly reduces tumor…
There are many evidences for the involvement of lipid mediators such as prostanoids and cholesterol derivatives in the modulation of inflammatory and…
The kinase GRK2 as a central node in cell signaling networks. Study of its interactome and implications in cardiovascular, inflammatory, diabetes/…
Our interest is the identification of the molecular regulators that control the physiological and pathological development of T and non-T (mainly…
We are interested in understanding how viruses evade the host immune response. We are characterizing herpesvirus and poxvirus proteins that interact…