Cell death in development and disease

Apoptotic microtubules network during the execution phase of apoptosis Selective mitochondrial degradation (mitophagy) in mitochondrial diseases

Mechanisms of gene regulation and biofilm development

Work in the group is focused on the study of molecular regulatory mechanisms in bacterial metabolism and biofilm development, and the application of…

Development of the hemato-vascular system and stem cells.

The general interest of the group is to understand the mechanisms involved in stem cell/progenitor cell differentiation during development and in…

Lipids and Cardiovascular Pathology

Study of the pathophysiological role of LRP1 in the cardiovascular system. Molecular mechanisms involved in the modulation of LRP1 expression and…

Vascular biology, atherosclerosis and cardiovascular remodeling

The major research activity of this group addresses the study of the vascular biology as well as the cellular and molecular mechanisms involved in…

Fungal and yeast biotechnology

During their life cycle, fungi are able to change their morphology in response to environmental conditions. Our group is interested in the…

Genetics and functional genomics of genes with small open reading frames

We are major contributors to the growing realization that hundreds of thousands of small ORFs (smORFs) of 10 to 100 amino-acids (aa) exist in every…

Development and evolution of the vertebrate skeleton

Our group uses the mouse limb skeleton as an experimental system to study the molecular and cellular mechanisms that coordinate morphogenesis and…

Cancer molecular targets

Our group is focused on the molecular mechanisms driving cancer progression, with particular emphasis in pancreatic cancer. This tumor, in particular…

Cardiac rhythm and contraction

Our group focuses on patho-physiological aspects of cardiac excitation-contraction coupling and arrhythmogenesis. Our goal is to improve the…