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In our laboratory we aim at understanding the mechanisms underlying NERVOUS SYSTEM development, understanding DEVELOPMENT as the whole process in an…
Pre-mRNA processing or splicing is an essential step of eukaryotic gene expression, where the spliceosome removes introns and exons are sequentially…
The group launched the molecular diagnosis of breast / ovarian cancer and hereditary colorectal cancer using the technique HA_CAE. In addition to the…
Study of the experimental conditions that will increase the frequency of gene targeting in human cells by testing different viral vectors and…
Molecular genetics, genomics, transcriptomics and cell biology of thyroid cancer genesis, maintenance and progression, with especial emphasis on…
During their life cycle, fungi are able to change their morphology in response to environmental conditions. Our group is interested in the…
We are major contributors to the growing realization that hundreds of thousands of small ORFs (smORFs) of 10 to 100 amino-acids (aa) exist in every…
Our group uses the mouse limb skeleton as an experimental system to study the molecular and cellular mechanisms that coordinate morphogenesis and…
In vivo implementation and optimization of different CRISPR-Cas systems using zebrafish as model system.
Applying CRISPR-Cas and other molecular and…
We are a multidiscplinary laboratory that combines theory and experiments to understand the mechanisms that control embryonic self-organization. The…