Rare diseases related to autophagy and intracellular trafficking defects

Study of autophagy and its regulation at the molecular and cellular levels. Roles of autophagy in rare diseases.

Molecular mechanisms of mitochondrial physiopathology

Novel targets in neurodegeneration and cancer

NANOIMMUNOLOGY of T Lymphocyte activation and apoptosis.

Study of the mechanisms involved in the polarised traffic of MVBs/lytic granules and their role in the secretion of exosomes by T lymphocytes…

Biomedical Magnetic Resonance (MRBIO)

Magnetic resonance imaging (MRI) and spectroscopy (MRS) allow non-invasive visualization of physiological and pathological processes at the molecular…

Physiopathology and molecular mechanisms of obesity and related comorbidities.

Insulin resistance is an early event in type 2 diabetes (T2D) and is closely linked to obesity and immunometabolism. In obese individuals, gut…

Redox bioenergetics, mechanisms and physiology

he Metabolic Syndrome is associated with an increased risk of developing an important number of prevalent diseases, including cardiovascular diseases…

Translational Research in Breast and Gynecological Cancer (Ovarian and Endometrial Cancer)

The main research interest of the group is to provide deeper knowledge of the novel resistance, tumor invasion and metastasis mechanisms in solid…

Colon cancer: organoids, microenvironment and vitamin D

Our group studies human colon cancer. We use primary cultures of fibroblasts and stem cell-derived organoids established from healthy and tumor…

Cell senescence and tumour suppresion

Study of mechanisms and genes involved in anti-tumour protection in mammals, with a special focus on cellular senescence.