Colon cancer: organoids, microenvironment and vitamin D

Our group studies human colon cancer. We use primary cultures of fibroblasts and stem cell-derived organoids established from healthy and tumor…

Cell senescence and tumour suppresion

Study of mechanisms and genes involved in anti-tumour protection in mammals, with a special focus on cellular senescence.

Genetics and Pathophysiological Mechanisms of Congenital Anomalies

The research activity of our group is focused on the identification of new genes responsible for rare developmental disorders and the study of the…

Traslational Oncology: Microbiota and Neoplasic Development

Chormosome Instability and Tumorigenesis

Gastric cancer (GC) is still the fourth main cause of cancer related death all over the world. Its high prevalence and the lack of efficient…

Telomere diseases and experimental therapies

Most of our projects are centred in the study of rare diseases related to the maintenance of the telomeres, named telomeropathies or telomere biology…

Molecular control of metabolic homeostasis

Our work is focussed on the study of the molecular mechanisms that regulate the development, cell differentiation and function of pancreatic islets.…

Hearing Neurobiology and Myelinopathies

Study of the molecular basis of hearing, pathology of hypoacusis and myelinopathies Hearing loss is one of the most prevalent medical problems. It is…

Biological and Environmental Proteomics

Research and development in methods and technologies related to the study of protein expression in humans and other organisms. Main areas of research…

Hemostasis and immunity

The group studies the contribution of vitamin K-dependent proteins and their receptors in human pathology. The processes of coagulation and immune…