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Small molecule that stabilizes the retromer complex, showing strong neuroprotective effects in highly excitotoxic conditions and maintaining key…
Study of the pathophysiological role of LRP1 in the cardiovascular system. Molecular mechanisms involved in the modulation of LRP1 expression and…
The major research activity of this group addresses the study of the vascular biology as well as the cellular and molecular mechanisms involved in…
Cancer stem cells (CSCs), also known as tumor-initiating cells or tumor-propagating cells, constitute a biologically unique subset of stem-like cells…
Cilia are microtubule-based plasma membrane protrusions emanating from a specialized centriole known as basal body. Conserved from unicellular…
Our group is focused on the molecular mechanisms driving cancer progression, with particular emphasis in pancreatic cancer. This tumor, in particular…
Our group focuses on patho-physiological aspects of cardiac excitation-contraction coupling and arrhythmogenesis. Our goal is to improve the…
The main interest of the Cell Cycle…
Our laboratory is interested in understanding the cellular and molecular immunological mechanisms of autoimmunity and cancer. Specifically, we focus…
The aging of the population poses a growing burden in society. This is associated with an increase in disability and diseases that have a high impact…