Neuroprotective strategies

Relevance of antioxidant and anti-inflammatory defense in neurodegenerative diseases

Hypoxia and angiogenesis

The fundamental objective of our group is to deepen our understanding of the molecular machinery of the hypoxia response. Specifically, we seek to…

Bioinformatics and computational biology of cancer evolution

Bioinformatics and computational biology: development and implementation of methods for the analysis of high-throughput data, mainly in evolutionary…

Diagnostic and neuroprotective tools for excitotoxicity and brain ischemia

We are interested in the development of diagnostic strategies and neuroprotective drugs applicable to pathologies associated to the overactivation of…

Rare diseases related to autophagy and intracellular trafficking defects

Study of autophagy and its regulation at the molecular and cellular levels. Roles of autophagy in rare diseases.

Molecular mechanisms of mitochondrial physiopathology

Novel targets in neurodegeneration and cancer

NANOIMMUNOLOGY of T Lymphocyte activation and apoptosis.

Study of the mechanisms involved in the polarised traffic of MVBs/lytic granules and their role in the secretion of exosomes by T lymphocytes…

Biomedical Magnetic Resonance (MRBIO)

Magnetic resonance imaging (MRI) and spectroscopy (MRS) allow non-invasive visualization of physiological and pathological processes at the molecular…

Physiopathology and molecular mechanisms of obesity and related comorbidities.

Insulin resistance is an early event in type 2 diabetes (T2D) and is closely linked to obesity and immunometabolism. In obese individuals, gut…