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Our group has demonstrated experience in the functional characterization of surface proteins on tumour, leukocytic and endothelial cells, that have…
Mechanisms of infected cell recognition and in vivo control of viral infections by CD8+ cytotoxic T lymphocytes and use in vaccine development.
Our research focuses on the role of TCFL5, a bHLH transcription factor, in colon cancer cells. Deletion of TCFL5 significantly reduces tumor…
There are many evidences for the involvement of lipid mediators such as prostanoids and cholesterol derivatives in the modulation of inflammatory and…
The kinase GRK2 as a central node in cell signaling networks. Study of its interactome and implications in cardiovascular, inflammatory, diabetes/…
Our interest is the identification of the molecular regulators that control the physiological and pathological development of T and non-T (mainly…
We are interested in understanding how viruses evade the host immune response. We are characterizing herpesvirus and poxvirus proteins that interact…
The laboratory works on designing and testing Parvoviruses as possible anticancer biological tools. The analyses are tackled from both molecular…
Molecular bases of RNA virus extinction by lethal mutagenesis and exploration of antiviral protocols using mutagenic agents and inhibitors.
We use protein engineering and biopphysical, biochemical and biological analyses to study the molecular structure, physical properties and biological…