Dendritic cell and macrophage immunobiology

Activation, cell cycle and apoptosis in autoimmunity and inflammation

Activation, proliferation and apoptosis are basic mechanisms for regulation of activated/memory T cell expansion, known as homeostasis. Our research…

Nanobiomedicine, cancer immunotherapy, and autoimmune diseases

The overall objective of our group is to understand nanomedicines-mediated molecular and cellular mechanisms in distinct biomedical applications…

B lymphocyte dynamics

The complexity of the B lymphocyte immune response involves changes in cell behavior, switching from highly motile states to stable cell-to-cell…

Stress-activated protein kinase p38MAPK in inflammation and cancer

The aim of our group is both to discover how members of the p38MAPK family regulate cellular function in physiological conditions and in response to…

Development of Antibody-Based Agents for Immunotherapy

Chemokines and their receptors are proteins involved in homeostasis of the immune system and inflammatory responses that are also involved in growth…

Signaling networks in inflammation and cancer

Identification and characterization of signaling pathways and molecules that regulate the inflammatory response, with a particular focus in solid…

Stem cells and immunity

Chemokine receptors: new targets for therapeutic intervention

Understanding the mechanisms of chemokine signaling and chemokine function with the aim to provide a clearer understanding of how this family of…

Lipid Signaling

The healthy immune system makes use of a variety of surveillance mechanisms at different stages of lymphoid development to prevent the occurrence and…