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Two repurposed drugs have been identified that act by inhibiting CCT, an essential chaperone in tumor proteostasis and the folding of key proteins…
Study of the pathophysiological role of LRP1 in the cardiovascular system. Molecular mechanisms involved in the modulation of LRP1 expression and…
The major research activity of this group addresses the study of the vascular biology as well as the cellular and molecular mechanisms involved in…
We applied a multidisciplinary approach including metabolic modelling, systems and synthetic biology to study bacterial metabolism from cellular to…
In January of 2015 I took possession of my position as Titular Scientist at CNB and in July 2016, the laboratory was equipped and staff trained and…
Adult stem cell populations are critical to maintain tissue function and, therefore, balanced self-renewal/differentiation, and the prevention of…
Hepatitis B virus (HBV) represents an important human pathogen causing both acute and chronic hepatitis. It is estimated that over 240 million people…
Life is dynamics. Living beings are out of equilibrium systems. Our lab is specially interested in dynamics that show regularities: oscillations when…
Our group is focused on the molecular mechanisms driving cancer progression, with particular emphasis in pancreatic cancer. This tumor, in particular…
Our group focuses on patho-physiological aspects of cardiac excitation-contraction coupling and arrhythmogenesis.
Our goal is to improve the…