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Small molecule that stabilizes the retromer complex, showing strong neuroprotective effects in highly excitotoxic conditions and maintaining key…
Two repurposed drugs have been identified that act by inhibiting CCT, an essential chaperone in tumor proteostasis and the folding of key proteins…
Cancer stem cells (CSCs), also known as tumor-initiating cells or tumor-propagating cells, constitute a biologically unique subset of stem-like cells…
Cilia are microtubule-based plasma membrane protrusions emanating from a specialized centriole known as basal body. Conserved from unicellular…
We applied a multidisciplinary approach including metabolic modelling, systems and synthetic biology to study bacterial metabolism from cellular to…
In January of 2015 I took possession of my position as Titular Scientist at CNB and in July 2016, the laboratory was equipped and staff trained and…
Adult stem cell populations are critical to maintain tissue function and, therefore, balanced self-renewal/differentiation, and the prevention of…
Hepatitis B virus (HBV) represents an important human pathogen causing both acute and chronic hepatitis. It is estimated that over 240 million people…
Life is dynamics. Living beings are out of equilibrium systems. Our lab is specially interested in dynamics that show regularities: oscillations when…
The main interest of the Cell Cycle…