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Two repurposed drugs have been identified that act by inhibiting CCT, an essential chaperone in tumor proteostasis and the folding of key proteins…
We applied a multidisciplinary approach including metabolic modelling, systems and synthetic biology to study bacterial metabolism from cellular to…
In January of 2015 I took possession of my position as Titular Scientist at CNB and in July 2016, the laboratory was equipped and staff trained and…
Adult stem cell populations are critical to maintain tissue function and, therefore, balanced self-renewal/differentiation, and the prevention of…
Hepatitis B virus (HBV) represents an important human pathogen causing both acute and chronic hepatitis. It is estimated that over 240 million people…
Life is dynamics. Living beings are out of equilibrium systems. Our lab is specially interested in dynamics that show regularities: oscillations when…
Virus evolution. Experimental evolution.
Viral emergence. Virological factors promoting cross-species transmission. Viral tropism mediated by…
Theory, Bioinformatics and Computation (formerly Dynamics of Living Systems) is a research group created in the new research institute I2SysBio (2017…
RNA viruses have the highest mutation rates of any organism, which allows them to evade immunity, escape antiviral therapy or vaccines, and emerge…