IMMUNOREGULATORY MECHANISMS IN THE DEVELOPMENT OF
CHAGAS DISEASE: TRANSLATIONAL APPLICATIONS

During 2021 and 2022, our research focused on: (i) further studying the role of the SLAMF1 immune receptor in Trypanosoma cruzi infection and…

UNCONVENTIONAL AUTOPHAGY IN HEALTH AND DISEASE

The laboratory's research focuses on understanding the role of autophagy, a cellular degradation process, in various biological contexts. Autophagy…

TCR DOMAINS IN T CELL DIFFERENTIATION AND
PATHOPHYSIOLOGICAL AND THERAPEUTIC RESPONSES

Our research focuses on understanding the mechanisms by which T cells recognize antigens presented by Major Histocompatibility Complex (MHC)…

ULTRAHIGH-THROUGHPUT DISCOVERY AND ENGINEERING
OF ENZYMES FOR BIOTECHNOLOGICAL APPLICATIONS

Microbial diversity is a rich source of genetic information with industrial potential, including biosynthetic gene clusters and novel enzyme…

Conjugation in Gram-positive bacteria

Bacterial conjugation is the process by which a conjugative element is transferred from a donor to a recipient cell via a pore connecting both cells…

Bacterial cell envelope during preseptal growth

VIRUS-CELL INTERACTION AND VACCINES DEVELOPMENT:
THE ASFV MODE

The African swine fever virus (ASFV) is a complex pathogen that affects pigs and wild boars, threatening the global pork industry. Our group…

Modulation of antiviral immunity by viral proteases and noncoding RNAs

The group is focused on i) the biotechnological applications of small RNA molecules mimicking structural domains in the noncoding regions of the FMDV…

NANOMEDICINE

The Nanomedicine@ICN2 group, established at the end of 2019, is dedicated to the development of nanomaterials and devices for therapeutic and…

Biotechnology of probiotics and intestinal pathogens

Our research focuses on the engineering of intestinal pathogens to better understand the infection processes that follow and how the immune response…