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A conjugate of fatty acids and amino acids has been found to protect neurons and facilitate the removal of protein aggregates that cause the most…
Polysaccharides, mimics of heparan sulfates present in cells, that are effective in treatment and prevention of viral infections. They act as a decoy…
Novel antiviral strategy targeting viral non-essential proteins (NEPs), scarcely prone to adaptive mutations. As a proof of concept, SARS-CoV-2 ORF9b…
New tiourea- and urea-based glycolipids with immunomodulatory activity. The compounds are Mincle agonist and have shown in vitro and in vivo…
Effective triple-negative breast cancer treatment based on the modulation of the phenotype of CD206+ tumor associated macrophages by means of a novel…
Design of a novel proteolytic set of chimeras (26STACs) directed at the degradation of the ceramide transfer protein CERT-1 by the proteasome, in an…
A recombinant gluten degrading protein that may have application as an agent or food additive for the prevention of gluten-mediated conditions, as…
Compounds useful as reversible light-regulated agonists for activation of Vitamin D receptor (VDR) using wavelengths suitable for phototherapy, that…
A new family of structural variants of the Aβ42 peptide capable of binding to the amyloid form of that peptide, thereby preventing its aggregation…
Family of compounds that exhibits in vitro antiprotozoal and antiviral activity, useful for treating diseases caused by protozoa, such as Leishmania…