Our research group is focussed on the study of relativistic jets, highly collimated fluids containing relativistic particles moving at velocities close to that of the speed of light that are present in multiple astrophysical sites, from active galactic nuclei, to gamma-ray bursts and microquasars.

Development, advanced characterization and theoretical studies of new porous materials for their employ in separation and adsorption processes of industrial or environmental interest and catalytic processes for removal of contaminants. Recentrly, we have launched a new research line focusses on the development of new materials with biocide and antifungical properties for fruits.

Group dedicated to the preparation and study of nanostructured metallic systems, focusing on novel physical properties and potential applications in the fields of communications (ICT), energy and health. We have vast and long experience both in the manufacture of microstructures and nanostructures using physical vapor deposition and micro- and nanolithography techniques, as well as in the characterization and modeling of their properties at the nanoscale.

Diabetes and obesity (metabolic diseases) are two major epidemics of the 21st century that constitute a major public health concern worldwide. The study of their pathophysiology can contribute to generate the novel knowledge for searching new treatments and therapies to counteract the impact of these chronic non-communicable diseases in patients.

Our laboratory is interested in the study of the signaling pathways and biological responses mediated by the lipid second messengers through the Rho GTPases. The activation of RhoGTPases is controlled by three groups of proteins: GEFs (guanosine exchange factors), GAPs (GTPase activating proteins) and GDIs (guanosine dissociation inhibitors). In our group we are studying a family of GAP proteins, the chimaerins.

Study of the experimental conditions that will increase the frequency of gene targeting in human cells by testing different viral vectors and modifying the expression of key protein in the repair of DNA lesions by using fusion proteins and specific siRNAs. We will use the most effective methods to correct mutations in primary cells from patients with monogenic diseases, particularly certain primary immunodeficiencies.

Living systems host a crowd of molecular chaperones that act with different mechanisms and serve to maintain protein homeostasis. Our group studies nuclear and cytosolic chaperones. Among the cytosolic chaperones we are interested in members of the Hsp60, Hsp70 and Hsp100 families.

Our research, focused in different aspects of vascular biology, aims to establish the molecular mechanisms underlying the initiation, progression and complication of vascular pathologies characterized by an important inflammatory component and an exhacerbated vascular remodelling such as abdominal aortic aneurysm and atherosclerosis.

Our aim is the study of the mechanisms that regulate the functional differentiation of CD4+ T cells and their involvement in the development of autoimmune/inflammatory diseases. In particular, we will explore the role of the membrane-bound TGFbeta inhibitor BAMBI and of ApoE in these processess. Our final goal is the identification and characterization of new molecular targets and therapies in autoinmune/inflammatory diseases.