Study of the mechanisms of the innate and adaptive immune response of fish and how they are modified during infection with different pathogens. This knowledge leads to developments of long-lasting mass vaccination systems using specific adjuvants.

We investigate how viruses that infect animals and are capable of jumping to humans (zoonotic viruses) using the West Nile virus (WNV) as the main model. West Nile virus is a bird flavivirus transmitted by mosquito bites, which causes outbreaks of encephalitis in horses and humans. We also investigate other flaviviruses such as the dengue virus, the Zika virus or the Usutu virus. Thanks to this knowledge, we develop new vaccines, antiviral drugs and diagnostic systems to combat them.

Our group is focused on the study of the porcine immune system in relation to the prevention and immunopathogenesis of infectious diseases

This group develops virus-host interaction analysis applied to emerging viruses of concern from their economic, sanitary, and environmental impact. Proteomics and transcriptomics are used to identify gaps and develop preventive and therapeutic strategies against epizootic and zoonotic viruses from a "One Health" perspective. We are interested in the molecular mechanisms of viral pathogenesis and immune response mechanisms.

We investigate the impact of management practices on agroecosystem services, including crop productivity, soil fertility and biodiversity, arable weed diversity, carbon and nitrogen sequestration, and the control of greenhouse gas emissions, supported by the application of precision agriculture and new technologies such as AI.

The "Effects of Environmental Contaminants" group studies the mechanisms underlying the toxicity of emerging pollutants (nanomaterials, endocrine disruptors, biocides or mycotoxins), as well as their bioaccumulation, particularly in fish. Two approaches are followed to reach this aim: in vitro assays in cell lines and in vivo assays, in aquatic organisms (algae, daphnia and fish). Cell assays study the short- and long-term effect on cell viability, sublethal effects, and substance internalization.

The research is focused on the development and application of methodology for the analysis and evaluation of the behavior of organic contaminants in environmental and food matrices. The main lines of research of the group are: - Development and application of analytical methodology for the determination of organic contaminants in environmental and food matrices. - Application of nanoparticles and molecular imprinted polymers in the determination of organic contaminants. - Studies on the distribution, persistence, absorption and degradation kinetics of organic contaminants in different matrices