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Metals for a safe and sustainable society (MESO)

Metals for a safe and sustainable society (MESO)


The research activity of the group focuses on the development and optimization of metallic materials and manufacturing and forming processes in a sustainable manner, to improve the safety of individuals and the environment. The main activity of the group is carried out in the transport, energy and construction sectors. Among the metals, light alloys and their foams are considered, mainly aluminum, and high strength steels, together with reinforced or composite materials.
Main specialization

Viral Immunology: Therapies and Vaccines

Viral Immunology: Therapies and Vaccines


In the last decades, the mouse model tremendously contributed to the progress of research in immunology. The need for translational immunological research, the development of new animal models more adapted to the scientific question, and the acquisition of new knowledge in comparative immunology is increasing in importance every year. The main aim of the group is to provide insights into immunological host-pathogen interactions by studying pigs¿ immune system in the context of natural relevant viral infections, such as Influenza virus (IV) or African swine fever virus (ASFV).
Main specialization

Cryo-EM of macromolecular machines

Cryo-EM of macromolecular machines


Our group is interested in understanding how macromolecular machines control essential cellular functions. We rely on a blend of cryo-electron microscopy, x-ray crystallography, with biochemical and functional assays to help to understand these processes at atomic level.
Main specialization

Cell Signalling and Adhesion

Cell Signalling and Adhesion


Our group studies regulatory mechanisms of key signalling switches controlling growth and adhesion signals, which regulate important cellular processes such as cell proliferation, migration and survival. In cancer these signals are responsible for triggering tumour invasion and metastasis. We use structural techniques, such as X-ray crystallography and electron microscopy, in combination with biochemical and functional studies to understand at atomic level how specific growth and adhesion signals are regulated and to rationalise how oncogenic events result in their deregulation.
Main specialization

Agroecological innovation in vineyards (In-Vid)

Agroecological innovation in vineyards (In-Vid)


In Vid has as main objective to reduce the dependence of traditional agrochemicals on pest control and evaluate the sustainability of agrosystems in terms of management, with special emphasis on the vineyard. Our gruop develops two lines of research: (i) functional biodiversity of vineyards and multitrophic interactions and (ii) habitat modification and development of new bio-tools.
Main specialization

Cancer molecular targets

Cancer molecular targets


Our group is focused on the molecular mechanisms driving cancer progression, with particular emphasis in pancreatic cancer. This tumor, in particular pancreatic ductal adenocarcinoma (PDAC), is the third-leading cause of cancer-related death in the developed countries and it is one of the most aggressive human tumors. The 5-year patient survival is less than 2%. Currently, there is no effective therapy for this highly malignant tumor and identification of novel molecular targets is an urgent need.
Main specialization

BioRobotics

BioRobotics


We are a research team that aims to generate new knowledge and technological solutions oriented to understand and control human biological systems and their environmental interactions. Our main scientific interest is the analysis of the neuromusculoskeletal and cognitive systems that enable humans to produce movements and decisions.
Main specialization

Synaptic Plasticity and Astrocyte-Neuron Interations

Synaptic Plasticity and Astrocyte-Neuron Interations


Astrocytes, classically considered as supportive cells for neurons without a direct role in brain information processing, are emerging as relevant elements in brain physiology through their ability to regulate neuronal and synaptic activity. Yet, their role in fundamental processes of brain function remains unknown.
Main specialization