Structural Biology of Proteins

Our group has long-standing experience in the structural characterization of bacterial virulence factors and in proteins implied in antibiotic resistance. The two major research lines of the group are: (i) the molecular basis of Acinetobacter baumannii infection, a life-threatening pathogen, and (ii) the mechanism of carbohydrate recognition by lectins, which have been shown to be involved in cancer development. For this, we use X-ray crystallography and cryo-electron microscopy in conjunction with other biophysical and biochemical techniques to accomplish our goal.