Regulation of DNA Replication and DNA Damage Response
To maintain genome integrity, DNA must be protected from damage occurring during replication or induced by environmental agents. Different cellular mechanisms such us DNA repair, DNA recombination and DNA damage-checkpoints contribute to preserve DNA integrity and cell survival under conditions that produce DNA alterations. We are mainly interested in the DNA-damage checkpoint, and more specifically in the intra S-phase Checkpoint, which is essential to preserve cell viability after replication in the presence of DNA damage.
Main specialization
Área de investigación:
Disciplina ERC:
- LS - LIFE SCIENCES
- LS1 Molecular and Structural Biology and Biochemistry
Industrial Leadership:
- 7. Other
- 7.1. Other
Societal Challenges:
- 1. Health, demographic change and wellbeing
- 1.01. Understanding the determinants of health, improving health promotion and disease prevention