NEURORIGINS Lab: engineering neural diversity

The group studies the cellular and molecular mechanisms involved in the production of different types of neurons and glia. These mechanisms generate cell differentiation trajectories that result in different neuronal and glial types. We aim to mimic these cell specification trajectories in order to produce neuronal and glial types of therapeutic interest. These cell types would make it possible to replace cells that are lost in certain neurological disorders. We also generate disruptive genetic tools to better understand cell differentiation in the brain, and to mimic natural developmental pathways for the generation of cell types à la carte.