Microbiota metabolites from diet and health group (Microbolites)

The interaction between diet and gut microbiota has a profound impact on health. Diet modulates gut microbial communities both in terms of changes in their composition and genetic diversity. In turn, gut microorganisms determine the capacity of each individual to produce bioactive compounds from substrates present in food. Among the bioactive components of the diet, metabolites produced by the microbiota from food precursors are relevant players in the modulation of the host response to infection and in the modulation of inflammatory processes. Preliminary results in our group show that metabolites produced by human microbiota bacteria from dietary compounds modulate immune responses to infection and reduce the inflammatory consequences of infection and in diseases such as cancer and inflammatory bowel disease. In our research group we investigate the connections between microbiota, diet and health by focusing on the effects of metabolites produced by gut inhabitants on disease and hom