Functional Proteomics Group

Functional proteomics aspires to draw a complete map of protein dynamics, interactions and posttranslational modifications that take place in the cell. Our goals within the CNB Functional Proteomics Group is to develop and apply state of the art tools to monitor proteins involved in molecular interactions and pathways relevant to pathologies in a variety of tissues, cell types and organisms upon various experimental treatments/conditions. We are also incorporating latest technologies to specific functional proteomic projects: 1) Human Proteome Project: to systematically map the whole chr-16 human proteome. 2) Signal transduction networks untangled by phosphoproteomic analyses. 3) Interactomics of the Centrosome, 4) Computational proteomics: data analysis obtained from large-scale experiments and meta-annotations. 5) Quality control and experimental standardization and 6) prolamin characterization in foods by means of classical and mass spectrometry in the context of celiac diseases