Pancreatic Islet development and Regeneration Unit/Laboratory of Aging Biology (PIDRU LAB)

The long-term research goal of the PIDRU team is to translate our understanding of fundamental molecular mechanisms of pancreatic islet physiology to `drugable¿ targets for the development of innovative therapies for the treatment of Diabetes Mellitus. More specifically putative targets implicated in ß-cell regeneration as well as survival are being investigated using a combination of molecular and cellular tools with subsequent validation in animal models of diabetes. A Medicinal chemistry program is also being developed on promising candidates. Several candidate targets are in the pipeline.