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The long-term research goal of the PIDRU team is to translate our understanding of fundamental molecular mechanisms of pancreatic islet physiology to…
The key role of genome instability in tumorigenesis and a number of rare cancer-prone genetic diseases, as well as its potential risks in stem cell…
Research lines:
-Chromatin Remodeling and Gene expression
-Cancer epigenetics
-Epigenetic changes during cell differentiation and development
The "Chromatin integrity and Function" group is a basic research team whose main scientific aim is understanding the molecular mechanisms underlying…
The research group investigates 1) the molecular bases and treatment of rare diseases and 2) how oxidative Damage modulates DNA repair and…
The research in our group aims to advance in our knowledge about the signaling pathways that orchestrate the progression through the cell cycle, as…
DNA Double Strand breaks are the most citotoxic DNA lesions. When left completely unrepaired they cause cellular and embryonic lethality. However,…
Microtubule (MT) nucleation, the event that initiates de novo formation of MTs, is a highly regulated process that enables cells to acquire specific…