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New compounds to treat parasitic diseases such as Chagas disease, leishmaniasis and trypanosomiasias. These derivatives act on a new target: G-…
Study the genetic basis of autoimmune diseases though genomic approaches –genome wide association studies, epigenetics, whole gene expression…
T lymphocytes are characterized by the expression of a specific antigen receptors, TCR, composed by two chains: alpha and beta, or gamma and delta.…
To know the relationship between the central nervous system and the immune system, characterizing the connection between infectious diseases and…
Identification of regulatory variants and causal genes in multiple sclerosis and associated pathogenic activity. The identification of causal…
Our group is dedicated to the study of the function of signaling through the mechanism of post-transductional modification of proteins known as poly…
Our current research interest is in signal transduction and signaling molecules as drug targets or disease biomarkers. In our laboratory we have…
(a) Signaling by TCR, BCR, and membrane receptors; by co-receptors CD38 and CD19; and by "Toll-like receptors “TLR2 and TLR4. Study the role of…
The functional coupling of transcription and alternative splicing is emerging as an essential component of gene expression regulation. Despite…