Excitabilidad Neuronal

Our overall aim is to understand the nanoscale physiology of the brain. Hereunder the role of the brain extracellular space (ECS) in signalling and metabolite clearance through modulation of diffusion, and the integrated regulation by multiple partners of synaptic signalling, beyond the mere pre- and post-synapse pair. To pursue these research lines we combine electrophysiology and fluorescence imaging in live brain slices, allowing us to read out structure and function. We are enabled by our expertise in super-resolution STED microscopy, and our implementation of this technique in our lab.