- Instituto
-
- CENTRO NACIONAL DE BIOTECNOLOGIA
- Head researcher
- JOSE MARIA VALPUESTA MORALEJO
Structure and function of molecular chaperones
Our group is devoted to the structural determination of macromolecular complexes, among them molecular chaperones, proteins that assist the folding of other proteins.
We use mainly electron microscopy and image processing techniques, but we combine them with biochemical and molecular biology techniques, to structural and functionaly characterise various molecular chaperones, among them CCT, Hsp90, Hsp70, Hs40 and PFD, and cochaperones like PhLP, Hop, Hip and CHIP.
Our group is also interested in the use of single-molecule techniques, in particular optical tweezers, in collaboration with the group of Dr. Carrascosa.
Main specialization
Área de investigación:
Disciplina ERC:
- LS - LIFE SCIENCES
- LS1 Molecular and Structural Biology and Biochemistry
Industrial Leadership:
- 2. Nanotechnologies
- 2.1. Developing next generation nanomaterials, nanodevices and nanosystems
Societal Challenges:
- 7. Other
- 7.1. Other