STRUCTURAL & PHYSICAL DETERMINANTS OF VIRAL ASSEMBLY

We are interested in the structural and physical principles that govern assembly and stabilization of complex viruses. As a model system we use adenovirus, a challenging specimen of interest both in basic virology and nanobiomedicine, as well as other structurally related viruses. We approach the problem from an interdisciplinary point of view, combining Biophysics, Computational, Structural and Molecular Biology techniques. Sharing expertise and resources is a key pillar in our work. Accordingly, we keep a variety of intra- and extramural collaborations enriching the development and interpretation of our work.