Structural Biology of Host-Pathogen Interactions

The main goal of the ‘Structural Biology of Host-Pathogen Interactions’ group is the study of protein-protein and protein-small molecule interactions that vehicle the communication between the human host and the microbiota and the complement system and bacterial pathogens. To this end we use methods that range from recombinant protein and protein complex production technologies to X-ray diffraction and biochemical and biophysical characterization methods. The application of these methodologies allows us to analyse the two facets that explain the functional results of such interactions: the molecular architecture and the dynamic behaviour of the formed complexes.